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FACS assay shows that Biotinylated Human OX40, Avitag,His Tag (TN4-H82E4) can bind to HEK293/Human OX40 Ligand / TNFSF4 Stable Cell Line (CHEK-ATP054). HEK293/Human OX40 Ligand / TNFSF4 Stable Cell Line was red line, Negative control HEK293 cells was grey line (QC tested).
Loaded Biotinylated Human OX40, Avitag,His Tag (Cat. No. TN4-H82E4) on SA Biosensor, can bind Human OX40 Ligand Protein, His Tag (Cat. No. OXL-H5243) with an affinity constant of 91.3 pM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).
Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
Amlitelimab | KY-1005; SAR-445229 | Phase 3 Clinical | Kymab Ltd, Sanofi | Hidradenitis; Scleroderma, Systemic; Immune System Diseases; Lung Diseases, Interstitial; Asthma; Dermatitis, Atopic; Eczema | Details |
RP-3 | RP-3 | Phase 2 Clinical | Replimune Inc | Solid tumours; Liver Neoplasms; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Carcinoma, Hepatocellular | Details |
HS-130 | HS-130 | Phase 1 Clinical | Heat Biologics | Solid tumours | Details |
anti-cancer mRNA therapeutics (Moderna Therapeutics) | mRNA-2752 | Phase 1 Clinical | Moderna Inc, Astrazeneca Plc | Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Neoplasms; Carcinoma, Transitional Cell; Lymphoma; Lymphoma, Non-Hodgkin; Carcinoma, Non-Small-Cell Lung; Melanoma | Details |
IMB-101 (IMBiologics) | Phase 1 Clinical | IMBiologics Corp | Arthritis, Rheumatoid | Details | |
IBI356 | IBI356; IBI-356 | Phase 1 Clinical | Innovent Biologics(Suzhou) Co Ltd | Autoimmune Diseases; Dermatitis, Atopic | Details |
SAR-443726 | SAR-443726 | Phase 1 Clinical | Sanofi | Dermatitis, Atopic | Details |
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